Although many scientists today assume that Sanger was the first to figure out how to sequence DNA, that’s not the case. As with RNA, Sanger was edged out by a Cornell biochemist. This time it was Ray Wu, who, in 1970, published a method to “read” specific sections of two bacterial virus genomes, called λ and bacteriophage 186. Wu’s method was only capable of sequencing “cohesive ends,” short single-stranded sections of these particular phage genomes, and so wasn’t considered a “general” solution to the DNA sequencing problem. In 1974, Wu’s lab refined this technique into the first general sequencing method, but it proved extremely labor-intensive and failed to catch on.
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一、Anthropic与Cursor：效率奇迹背后的“人机新编队”1. 黄金时代的秘密：工作量必须碾压人数前谷歌、亚马逊资深工程师Steve Yegge在2026年2月发布的深度长文《The Anthropic Hive Mind》中，揭示了一个残酷公式：
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